ZSeeker: an optimized algorithm for Z-DNA detection in genomic sequences
Jan 2025·
,·
1 min read
G. wang
Equal contribution
Ioannis Mouratidis
Equal contribution
,K. provatas
Et al.
Abstract
Z-DNA is an alternative left-handed DNA structure implicated in gene regulation and genome instability. We developed ZSeeker, an optimized Python tool for detecting Z-DNA forming sequences in large genomic datasets with improved speed and accuracy.
Type
Publication
Briefings in Bioinformatics, 26(3)
ZSeeker provides researchers with a fast and accurate tool for identifying Z-DNA forming sequences across entire genomes, facilitating studies of genome regulation and stability.
Authors
Authors
Ioannis Mouratidis
(he/him)
Senior Research Engineer/Scientist Associate
Machine learning and genomics researcher with 35 publications (10 first or senior author).
Co-founded AI-driven cancer biomarker startup, authored grants securing $4M+ in competitive funding
and currently lead a 5-member team with a focus in developing novel computational methods and testing
the capabilities and safety profiles of biological foundation models.
Authors
Authors